Berlioz

He first went to Paris to study Medicine which he did not enjoy and then was disgusted by it because of dissecting a dead body. To his parents dismay he abandoned medical studies to do music. He created a symphony called Symphonie fantastique, which a friend rewrote to play on piano.

Michelangelo

Michelangelo's dad saw his son was good at drawing and made him an apprentice of a painter named Ghirlandaio. He lived with the Medicis for a while and learned to sculpt. Once he got famous the pope, Pope Julius II, had him paint the celing of the Sistine Chapel. He is famous for sculpting David, a statue meant to look like David from the Bible story of David and Goliath.

Amerigo Vespucci

Amerigo Vespucci was born in 1454, in Portugal. He was usually accredited for the discovery that America is actually a new continent. But the letters that he probably wrote and made him quite famous were probably accounts based on his voyages and may not have been written by him. One fact I found interesting was that Christopher Columbus held no ill will towards Vespucci. The letters I just talked about pointed to him having 4 voyages but there is not must information on the fourth or if there was even a fourth voyage.